QM 21 A Comprehensive Overview of Quantum Mechanics-Free Organic Chemistry

Inspired by the 2014 Nature Chemistry online publication “A comprehensive overview of chemical-free consumer products” [1], we have examined and subjected an exhaustive number of organic reactions [2-6] to Quantum Mechanics analysis. Herein are described all the organic reactions, to our knowledge, that do not involve Quantum Mechanics.


























1.Golberg, A.F.G. and Chemjobber, C.J. Nature Chemistry, 2014, “A comprehensive overview of chemical-free consumer products”

2.Organic Chemistry:

3.“Quantum Mechanics” Free Molecular Mechanics:

4.“Quantum Mechanics” contaminants in Semi Empirical methods:

5.Quantum Mechanics Free Particle:

6.Nesse, F. et al. J. Am. Chem. Soc. 2019, 141, 2814. Chemistry and Quantum Mechanics in 2019: Give Us Insight and Numbers.



Authors appreciate Nature Chemistry for pioneering word-free publications.


Author Statements

Richard Feynman (Physics Nobel prize, 1965) noted in The Character of Physical Law, “I think I can safely say that nobody understands quantum mechanics.” MIT Press, ISBN 987-0262533416. Analogously, authors acknowledge that we might not fully understand why the QM analyses came out as what they are as described in previous 20 chapters and future ones, yet it will not stop us from learning from it. QM doesn’t speak, it is an excellent teacher we cherish.


This article is written and edited by Qiuyue Wang, Yongsheng Chen, Zhong Zheng, and John S. Wai.


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