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人源细胞系异种移植瘤模型(CDX)

人源细胞系异种移植瘤模型(CDX)

 

  • 完备的人源细胞系异种移植瘤模型(CDX)
    • - 215个CDX肿瘤模型,包括相关SOC验证数据。
  • 世界领先的以荧光成像为基础的原位/转移肿瘤模型平台
    • - 28个荧光素酶标记的原位/转移CDX模型,包含16种肿瘤类型。

 

 

215个人源细胞系异种移植瘤模型(CDX)

 

Tumor types Cell lines
Bladder (7)  T24/83, RT112/84 , UM-UC-3, J82, HT1197, KU-19-19, VM-CUB1
Brain (5)  U87*, LN-229*, D283*, T98G*, U118MG
Breast (20)  Cal51*, BT-474*, HCC1954*, MDA-MB-231*, MDA-MB-468*, HCC1806*, MCF7*, HCC1937, MDA-MB-436*, SUM-52PE, JIMT-1*, MDA-MB-361*, HCC-70, SUM 159PT, MFM-223, T47D*, HCC1428, ZR-75-1*, MT-3, DU4475*
Cervical (2)  SW756, Ca Ski
Colorectal (19)  Colo205*, HT29*, HCT-116*, HCT-15*, LS180* , LS174T*, SW620*, HT55*, DLD-1, Lovo*, COLO-320DM, RKO, Caco-2, T84, WiDr, SW480, SW 48, LS411N, COLO 201
Duodenal (1)  HuTu80  
Esophageal (2)   T.Tn, OE21*  
Gastric (8)  NUGC4*, SNU-1*, SNU-16*, MGC-803, NCI-N87*, SNU-5, MKN45*, HS 746T  
Head & Neck (4)  Cal 27, RPMI2650, SCC-9, Fadu*
Leukemia (13)  HEL 92.1.7*, MV4-11*, CCRF-CEM,  HL-60, K562, KG-1, MOLT-4, Kasumi-1*, Nalm-6*, THP-1, SET-2 ,PL-21, MKL-1
Lymphoma (21)  Daudi*, SU-DHL-2*, SU-DHL-4*, SU-DHL-6, SU-DHL-10, Granta-519, Maver-1, Mino*, NAMALWA, Raji*, Ramos*, RL, WSU-DLCL2*, Z-138, U937, DoHH2*, Farage*, Pfeiffer, REC-1*, U2932, Toledo

Testicular Embryonal (1)

NEC14


 

Tumor types Cell lines
Liver (10)  BEL-7404*, Hep3B*, Huh 7*, HepG2, SNU-182, QGY-7703, SNU-398, JHH-7*, MHCC97H*, SK-HEP-1*
Lung (48) NCI-H1650, NCI-H226, NCI-H460, PC9*, A549*, Calu-1, Calu-6*, EBC-1, A427*, NCI-H647, MSTO-211H,  NCI-H292*, NCI- H322, NCI-H358*, NCI-H441*, NCI-H520, NCI-H1975*, NCI-H2228*, SK-MES-1, NCI-H1299, HCC-827*, HCC4006, NCI-H1703, NCI-H727, NCI-H2122*, DV-90, NCI-H69*, NCI-H1417*, NCI-H446, NCI-H526*, NCI-H82, SHP-77 , Calu-3*, NCI-H2170, NCI-H820*, NCI-H23, NCI-H1568, NCI-H1944, NCI-H2023, NCI-H2030, NCI-H2126, NCI-H838, NCI-H1838*, DMS114*, NCI-H211*, NCI-H209*, NCI-H2286, NCI-H596
Lung (Small cell, 10) NCI-H69*, NCI-H1417*, NCI-H446, NCI-H526*, NCI-H82, SHP-77, DMS114*, NCI-H211*, NCI-H209*, NCI-H2286
Melanoma (6) A375*, SK-MEL-24, SK-MEL-28, COLO 829*, SK-MEL-5 , MDA-MB-435S, MeWo
Myeloma (7)  KMS-28BM, KMS-11, MOLP-8*, NCI-H929, RPMI 8226*, MM.1S*, OPM-2
Neuroblastoma (4)  CHP-134*, SK-N-AS*, BE(2)-C*, SH-SY5Y
Ovary (5) A2780*, SK-OV-3*, ES-2*, OVCAR-3, TOV21G
Pancreas (9)  BxPC3*, Mia-pa-ca-2*, KP4*, PANC-1*, CAPAN-1,    Panc 02.13*, AsPC-1, HPAC, HPAFII
Prostate (5) PC-3*, DU145*, LNCap*, VCaP , 22RV.1*
Renal (5)  786-O*, ACHN, Caki-1, SK-NEP-1, A498
Sarcoma (11) HT1080, A673, KHOS/NP, 143B, SJSA-1* , SAOS-2, A204, G401, Aska-SS, HS-SY-II , Yamato-SS
Skin (1) A431*
Thyroid(1) TT


*:通过SOC化合物验证

 

 28个荧光素酶标记的原位/转移CDX模型

 

  • 包含16种肿瘤类型;
  • SPF级动物房内的小动物荧光成像系统。

 

 

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