Macrocyclic Chemistry

Macrocyclic Compound


  • Rich Experience (>15 years) on Construction of Versatile Macrocyclic Compounds, more than 8 representative cyclization methods have been developed.

  • Macrocyclic Cpds such as lactam, lactone, sulfonamides, ethers, Bi-cyclic & tri-cyclic, etc. can be efficiently synthesized, more than 1500 macocyclic compounds have been prepared and >30 g of desired products with 20-31 steps have been obtained.

  • More than 30 experienced chemists work on this platform.



Selected Reference Reported Macrocyclic Drug Compounds


Org. Lett. 2019, 21, 975; J. Med. Chem. 2018, 61, 3350; J. Med. Chem. 2019, 62, 10258



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